The New Vit C, Biogenic-C from GreenCow Company
 Even a great formulation would have limited value if the ingredients cannot get where they need to go. Besides being the only formulation that turbo assists the body’s own cellular antioxidant defense system, GreenCow Biogenic Vit C nutritional supplement uses the patent pending formula which has a novel oral cavity delivery system, a Chewable Tablet formulated to dissolve in the mouth to maximize absorption of the synergistic cellular partners (it should be sucked on like candy and allowed to dissolve slowly). This delivery system allows the key ingredients to be absorbed directly into your blood stream efficiently through the mouth’s buccal cells, effectively bypassing the gastro-intestinal tract, where bioavailability of the key ingredients are drastically reduced.
 GreenCow Biogenic Vit C is bio-science & technology combined to bring you The First Oral Chewable Vit C with Stevia, Calamansi and Goji. Slows and reverses aging at any age by rebuilding your collagen supply, building ligaments, bones, tissues, muscles and protects against cardio-vascular disease, cancer and diabetes complications, with no drug or herb mal-interactions. GreenCow Biogenic Vit C is a Chewable Tablet, formulated to dissolve through the lining of the mouth (buccal mucosa) and under the tongue (sub-lingual), bypassing gastrointestinal tract absorption, allowing key ingredients to be absorbed directly into your blood stream.
Only 1 Chewable Tab a day supplies more than the required daily allowance of Vit C. All you have to do is suck it like a candy. No more mega doses of Vitamins and Minerals. We guarantee you greater results. For Viral attacks like Dengue, H1N1, Flu, and its complications, take 3 – 4 or more Lozenges a day. There is no overdose.
Comparative Analysis
Research-based analysis on the peak blood levels and bio-availability of different drugs and vitamins when taken sub-lingually vs orally.
Drugs and Vitamins Sub-lingual Oral
Peak Blood levels 15 min 90 min
% bio-availability 60 - 90 % 1.2 - 5 %
GreenCow Biogenic Vit C
250 mg 250x90% 225 mg {sub-lingual}
(Chewable Tabs candy, sodium ascorbate with Stevia, Calamansi, Goji, alkaline)
Ordinary Vit C 500 mg
500x5% 25 mg {oral}
(capsule, sod ascorbate, alkaline)
- The GreenCow Biogenic Vit C is the more effective Vit C because it is 9X times more bio-available than ordinary Vit C, despite being only 250 mg.
- GreenCow Biogenic Vit C has a peak blood level time of only 15 min and that is 6X times faster than Ordinary Vit C in caps or tabs with a peak blood level time of one and a half hours.
- GreenCow Biogenic Vit C comes loaded with an impressive array of Vit C carrying herbs and fruit and berry in an advanced form of chewable tabs candy delivery (patent pending) system. The synergy alone wallops a pack of anti-oxidants and dense nutrients giving adults and kids that edge in combating viruses, bacteria and fungi all day long and all night long!
Definition and meaning of “BIOGENIC”…
..essential for maintaining the fundamental life processes;
Example:
"sleep and food and water are among the biogenic needs of the organism"
References :
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Wikipedia
Sublingual, literally 'under the tongue', from Latin, refers to a pharmacological route of administration in which certain drugs are entered directly into the bloodstream via absorption under the tongue.
Many pharmaceuticals are prepared for subligual administration. These commonly include cardiovascular drugs, steroids, barbituates, some enzymes and increasingly frequently, certain vitamins and minerals.
The principle behind sublingual administration is fairly simple. When a chemical comes in contact with the mucous membrane, or buccal mucosa, it diffuses into the epithelium beneath the tongue. This region contains a high density of blood vessels, and as a result, via osmosis, the substance quickly enters the blood stream at the sublingual artery. Quickly thereafter, the substance is carried by blood flow to the connected lingual artery, which takes up the chemical and translates it to its source: the carotid artery. This artery is connected directly to the brain.
In theory, sublingual routes of administration have certain advantages over simple oral administration. This route is often faster, and entering a drug into one's body sublingually ensures that the substance will only come in contact with the enzymes in saliva prior to entry into the bloodstream. Drugs otherwise orally administered must instead rely upon the incredibly hostile environment of the gastrointestinal tract. This may mean a much greater percentage of the original substance is degraded either by the myriad of enzymes in the GI tract, such as monoamine oxidase, or the strong acids it contains. Additionally, after GI absorption, the drug is sent to the liver where the drug may be extensively metabolized; this is known as the first pass effect of drug metabolism. Due to the degradative qualities of the stomach and intestine, or the solubility of the GI tract, certain substances, such as salvinorin A may only be administered orally via the sublingual route.
http://en.wikipedia.org/wiki/Sublingual
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Sublingual drug delivery refers to any method of administering medicine so that it can be absorbed directly into the bloodstream through the rich layers of blood vessels found on the bottom of the tongue. Compared to commonly used tablets, capsules and other oral dosage forms, sublingual absorption is generally much faster and more efficient. Products passing through the digestive tract are subject to a "first pass" effect, in which many of the ingredients may be broken down by stomach acid or metabolized by the liver.
Peak blood levels of most products administered sublingually are achieved within 10-15 minutes, which is generally much faster than when those same drugs are ingested orally, which is up to 90 minutes.
Sublingual absorption is efficient. The percent of each dose absorbed is generally higher than that achieved by means of oral ingestion.
http://www.gelstat.com/oradose.asp
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A drug placed between the gums and cheek (buccal administration) or under the tongue (sublingual administration) is retained longer so that absorption is more complete.
http://www.merck.com/mrkshared/mmanu...er298/298b.jsp
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The absorption mechanism under the tongue is different than that in the GI tract. Materials absorb directly into the circulatory system under the tongue; they do not pass to the liver and then out into systemic circulation.
http://www.chemcases.com/pheno/pheno14.htm
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There is considerable evidence that most sublingual substances are absorbed by simple diffusion; the sublingual area acting rather like litmus paper, readily soaking up the substances. However, not all substances are permeable and accessible to the buccal mucosa. The mucosa functions primarily as a barrier - similar to skin. But while it was once believed that the barrier of human skin was 'impenetrable' it is now recognised that the dermis is a good site for the absorption of many substances (eg, vitamins E & C creams; hormones; nicotine patches) and it is a growing field of endeavour.
Similarly the buccal mucosa presents an ideal site for absorption.
This potential continues to be explored for the administration of many drugs - providing many useful studies and a better understanding of the modus operandi - although the benefits of the less intrusive nutrition therapies have had little opportunity as yet to be as thoroughly researched.
One of the best known drugs used regularly with great success is Glyceryl Trinitrate - a potent coronary vasodilator which is used for the rapid symptomatic relief of angina. It has been found impressively effective when administered sublingually; pharmacologically active after only 1 - 2 minutes.
Impressive absorption has been attained with sublingual administration of desoxycortisone acetate, morphine, captoprill, nifedipine and 17-B Oestradiol - interestingly, it has also been shown that the sublingual administration of 17-B Oestradiol requires only 1/4 of the oral dose.
http://www.positivehealth.com/permit...alth/lea13.htm
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Sublingual Absorption
Some drugs are taken as smaller tablets which are held in the mouth or under the tongue. These are buccal or sublingual dosage forms. Buccal tablets are often harder tablets (4 hour disintegration time), designed to dissolve slowly. Nitroglycerin, as a softer sublingual tablet (2 min disintegration time), may be used for the rapid relief of angina. This method is also used for some steroids such as testosterone and oxytocin. Nicotine containing chewing gum may be used for cigarette smoking replacement.
Advantages:
First pass - The liver is by-passed thus there is no loss of drug by first pass effect for buccal administration. Bioavailability is higher.
Rapid absorption - Because of the good blood supply to the area absorption is usually quite rapid.
Drug stability - pH in mouth relatively neutral (cf. stomach - acidic). Thus a drug may be more stable.
Disadvantages:
Holding the dose in the mouth is inconvenient. If any is swallowed that portion must be treated as an oral dose and subject to first pass metabolism.
Only small doses can be accommodated easily.
http://www.boomer.org/c/p1/Ch07/Ch0703.html
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Sublingual absorption is 3 to 10 times greater than oral administration absorption and is only surpassed by hypodermic injection.
http://www.healingpeople.com/store/biomax.html
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If you take EDTA sublingually (under the tongue), your absorption level compared with oral chelation goes from 5-18 percent absorption for oral capsules to 60 percent for sublingual absorption. http://www.naturodoc.com/mm5/merchan..._Code=Vitamins
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Vitamin B-12 studies show that Sublingual B-12, B-6 & Folic Acid is readily absorbed into the bloodstream, raising blood levels on average by 90%. B-12 that is taken orally, not sublingually, only increases blood levels by 1.2%.
http://www.home-base-business-adviso...ngual-b12.html
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Sublingual absorption of selected opioid analgesics.
Weinberg DS, Inturrisi CE, Reidenberg B, Moulin DE, Nip TJ, Wallenstein S, Houde RW, Foley KM., Department of Neurology, Memorial Sloan-Kettering Cancer Center, New York, NY.
Ongoing interest in the improvement of pain management with opioid analgesics had led to the investigation of sublingual opioid absorption. The present report determined the percent absorption of selected opioid analgesics from the oral cavity of normal subjects under conditions of controlled pH and swallowing when a 1.0 ml aliquot of the test drug was placed under the tongue for a 10-minute period. Compared with morphine sulfate at pH 6.5 (18% absorption), buprenorphine (55%), fentanyl (51%), and methadone (34%) were absorbed to a significantly greater extent (p less than 0.05), whereas levorphanol, hydromorphone, oxycodone, heroin, and the opioid antagonist naloxone were not. Overall, lipophilic drugs were better absorbed than were hydrophilic drugs. Plasma morphine concentration-time profiles indicate that the apparent sublingual bioavailability of morphine is only 9.0% +/- 11.9% (SD) of that after intramuscular administration. In the same subjects the estimated sublingual absorption was 22.4% +/- 9.2% (SD), indicating that the sublingual absorption method may overestimate apparent bioavailability. When the oral cavity was buffered to pH 8.5, methadone absorption was increased to 75%. Thus, an alkaline pH microenvironment that favors the unionized fraction of opioids increased sublingual drug absorption. Although absorption was found to be independent of drug concentration, it was contact time dependent for methadone and fentanyl but not for buprenorphine.
These results indicate that although the sublingual absorption and apparent sublingual bioavailability of morphine are poor, the sublingual absorption of methadone, fentanyl, and buprenorphine under controlled conditions is relatively high.
http://www.ncbi.nlm.nih.gov/entrez/q...&dopt=Abstract
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Original Viagra is absorbed through the gut and takes 60-90 minutes to take effect, thereby eliminating any spontaneity in the sexual encounter. Sublingual absorption revolutionized the speed of Sildenafil Citrate. The new process decreases the time for the drug to be absorbed and weave its magic to as little as 15-20 minutes.
The beneficial effect of the Lozenge form is that you have considerably more control over when and how you decide to have sex.
http://www.soft-up.com/
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Sublingual absorption begins in the mouth - under the tongue and through the cheek
Homeopathic remedies are administered by sublingual absorption. This requires them to be sprayed under the tongue where they are absorbed directly into the bloodstream, bypassing the digestive tract. http://www.avon.com/avonfaq/default....eopathy+Sprays
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Clark, A.J. 1923. Properties of certain `colloidal' preparations. British Medical Journal. 1: 273-277.
`The suggestion is often made that metals in the colloidal form will continue to circulate for a long time in the blood: this is incorrect, as several workers have shown. Duhamel found that when colloidal silver was injected into a rabbit 60 per cent of the metal injected was fixed in the liver within fifteen minutes. Voight, in similar experiments, found that after three hours 81 per cent of the silver was fixed in the liver, and that none of it remained in the blood. It appears from these experiments that colloidal metals will not circulate in the blood and act there as a disinfectant for more than a few minutes.'
http://www.geocities.com/silver99rob/cs6.htm
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